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How Safe are Artificial Baby Milks?

Carol is currently the Canterbury Cot Death Research Fellow. The Canterbury Medical Research Foundation funds this research position. The following is a summary of the main points of Carol’s article, the full text and references of which can be found in LLLNZ’s Breastfeeding Communiqué 2003.

  • Artificial formula is an inert product compared to breast milk, which is a species specific, living fluid containing many essential growth and immunological factors that are unable to be reproduced in artificial baby milks.
  • Formula manufacturers are not required to constantly justify their products compared to the protection, promotion and support of breastfeeding that breastfeeding advocates are continuously forced to engage in.
  • The attempt to make artificial baby milks (ABMs) more like breast milk by the addition of long chain polyunsaturated fatty acids (LCPUFAs) needs further, more extensive, ‘non-formula industry’ research to determine if this is an improvement for all babies or if problems occur with this practice.
  • Some ABMs contain genetically modified (GM) components (soy, yeast based) but parents are generally unaware of this. Similarly they are also generally unaware of the availability of organic formula. Health professionals could be more proactive in providing information on these products.
  • There is a lack of research into the long-term implications and effects of using GM technology in ABMs and in particular of the impact on vulnerable developing baby brains.
  • GM techniques may give rise to new toxins (possibly from pesticide residues) and to risks of allergies and antibiotic resistance.
  • No maximum allowable amounts of ingredients are specified for ABMs. This overlooks an important safety factor in baby nutrition as babies could be overloaded with some ingredients.
  • The Australian College of Midwives submission to the 1999 ANZFA (Australia, New Zealand Food Authority) review of infant formula stated “any artificial formula sold with ‘novel ingredients’ should carry large warning messages that the ingredient is experimental and the appropriate consent arrangements be put in place for its use, consistent with other medical clinical trials in humans”.  If ABM is treated as ‘nutrition only’ clinical trials may not be subjected to as rigorous a review process as trials with recognised medications.
  • Attempts have been made within the current review (not yet released) of the New Zealand interpretation of the World Health Organisation’s International Code of Marketing of Breast Milk Substitutes, to increase the defined age range of an infant, from birth to six months old, to birth to one year old. This would increase protection for breastfeeding. Follow on formula is a most successful marketing initiative for ABM and is not covered by the New Zealand interpretation as it is designed for babies over six months old. Free samples can be sent to mothers of breastfeeding babies over six months old, which can negatively impact on breastfeeding by promoting the idea that breast milk becomes inadequate after six months of age. The New Zealand Infant Formula Marketers’ Association Code of Practice should provide more protection for breastfeeding.
  • The United Nations Convention on the Rights of the Child (UNCROC) 1989, to which New Zealand is a signatory, calls on state parties to always act in the “best interests of the child”. It enshrines the “right of the child to the enjoyment of the highest attainable standard of health” and the obligation to “ensure that all segments in society, in particular parents … are informed, have access to education and are supported in the use of basic knowledge of child health and nutrition, (and) the advantages of breastfeeding”. Some of this obligation falls on health professionals.
  • The decline of breast milk banks occurred after slower and supposedly inadequate growth rates were noted in babies fed on banked breast milk. This resulted in the production of special preterm formulas. Human milk fortifiers based on cow’s milk were later developed to add to expressed breast milk at the expense of research into the use of lacto-engineering of human milk to produce blends suitable for very low birth weight babies. There is an absence of evidence of the long-term benefit or deleterious effects of supplementation with multicomponent human milk fortifiers.
  • Powdered milk products are not sterile and are susceptible to bacterial contamination, (eg Enterobacter sakazakii which may cause meningitis, septicaemia and necrotising enterocolitis). These are very serious infections in neonatal intensive care units where babies are particularly vulnerable. Research by United States Food and Drug Administration (FDA) that showed E. sakazakii could be recovered from 14% of 141 samples of infant formula products. (Update: In August 2004 a premature baby in Hamilton NZ died as a result of E. sakazakii infection).
  • The establishment of human milk banks to supply screened, pasteurised donor breast milk would provide a safer more nutritionally suitable option for babies whose mothers are unable to produce enough of their own milk.
The use of ABM will still be necessary in some situations but stringent labelling and monitoring of these products is essential. Companies should be required to declare the sources of ingredients, including whether any genetically engineered ingredients are being used. Maximum allowable levels of ingredients should also be established and regulated.

 

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